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December 20, 2024

Fatigue refers to a state of prolonged or temporary physical or mental weakness and exhaustion, often accompanied by a lack of energy, motivation, and attention. It can be caused by various factors, including excessive physical activity, prolonged cognitive or emotional stress, inadequate sleep, poor nutrition, chronic illnesses, medication side effects, and more, severely impacting people's health, quality of life, and work efficiency. Nowadays, fatigue is not only a suboptimal state of health but can also lead to a range of diseases such as Alzheimer's disease, obesity, anxiety disorders, poor sleep quality, and depression.

Many herbs and plant extracts have traditionally been used to enhance physical endurance and increase vitality. These natural products may contain active compounds such as antioxidants, adaptogens, and neuroprotective agents, which help alleviate fatigue and restore energy, but have not been developed enough as new anti-fatigue nutritional supplementsSchisandra chinensis, also known as Wu Wei Zi, is a medicinal and edible plant native to China. It is rich in various bioactive components and possesses significant pharmacological activitiesThe main active components of Schisandra chinensis include polysaccharides, lignans, volatile oils, phenolic acids, triterpenes, and flavonoids. Among them, polysaccharides are the main active ingredient in Schisandra chinensis, primarily composed of mannose, galacturonic acid, glucose, galactose, and arabinose. Research has confirmed that Schisandra chinensis polysaccharides possess significant antioxidant, immune-regulating, anti-tumor, hypoglycemic, and lipid-lowering effects. Therefore, according to recent research, Schisandra chinensis extract could be considered as a potential anti-fatigue nutritional supplement in functional foods, beneficial for alleviating exercise-induced fatigue.

www.sciencedirect.com/science/article/abs/pii/S2212429223007800